I specialize in providing access to RGCC testing and/or creating personalized holistic integrative nutritional metabolic therapy for oncology clients via Telehealth.
Therapies are integrated with application of scientific data from RGCC (Research Genetic Cancer Centre) testing that enables personal customization of case management to achieve maximal positive clinical outcomes
Dr. Donato started featuring a Question & Answer Session in the YouTube Channel, AskDrMiven, on May 13, 2024. The topics covers RGCC testing. Dr. Donato will take questions from the comment section of the video posts as well as questions sent to AskDrMiven@pm.me, and will answer them in the next video podcast posted once a week. The video podcast is meant for public education and not a diagnosis and treatment advice. Subscribers are welcomed to the channel.
You can connect with Dr. Donato in Minnect, a mobile app that enables you to get professional answers quickly.
There are three options for engagement: 1) Send a text message and quickly get a text response. A text message can include RGCC testing or interpretation of a test result or a cancer question as it pertains to holistic and/or integrative therapy approaches. 2) For a more unique answer to your question, Dr. Donato can also send a personal video response. 3) For in-depth questions, you can book a video call.
To use the Minnect app, go to the App Store in your mobile device and download Minnect or Click Here. Create a User Account by clicking the "Sign Up" button below the "Login" button on the Login Screen. Login if you already have an account.
When you have logged in the Minnect app, in the question box at the top where it prompts "Find an expert...", enter my first name "Miven" or last name "Donato". This will take you to the page where you can connect with me. You can also navigate at the bottom of the app to "Chats" or "Calls".
The services offered by Dr. Donato, LLC is not to diagnose, treat, or cure a disease. Dr. Donato does not give medical advice. If you need a medical diagnosis and treatment, or if you have an urgent medical condition that needs medical care, please consult your primary care doctor.
You can order RGCC Testing through Dr Donato LLC without an appointment!
The major advantage to order RGCC testing without making an appointment is its cost-saving feature. In almost all cases, getting RGCC testing requires an office visit with an RGCC practitioner, which requires a consultation that may involve onboarding as a client first. The cost of onboarding as a client can be very significant. The nearest RGCC practitioner office may require significant transportation time and cost.
By getting the test ordered without a consultation enables the customer to decide later to become an established client for case management or to select an RGCC practitioner of his or her own choice. Also the customer may already have an RGCC practitioner but prefers not to do a consultation first in order to get RGCC testing done. Whatever the reasons, in the end customers have their choice to decide what to do with the test results.
To get the RGCC testing done, scroll down to How to Order Your Own RGCC Blood Tests.
Dr. Miven Donato graduated from Palmer College of Chiropractic in Davenport, Iowa (2001) with a Doctor of Chiropractic (DC) degree. He also has a Doctor of Physical Therapy (DPT) degree from Creighton University in Omaha, Nebraska (2009). His undergraduate degrees include a BSc in Physical Therapy from Loma Linda University (1990) and BSc in Medical Technology/Clinical Laboratory Science from Union College/Florida Hospital (1987). His solo practice in 2001 started with emphasis in orthopedic and sports therapy including dietary, health fitness and lifestyle medicine.
In 2010, Dr. Donato began to focus his practice in nutritional therapy. In 2012, he completed certification as a Gerson Practitioner at the Gerson Institute. Soon after he became an instructor for the Gerson Practitioner Training Program and was instrumental in starting the new distance-based online program in 2015. By 2018, he narrowed his scope of professional specialization to holistic integrative nutritional oncology care.
2018 was also the year Dr. Donato was introduced by a professional colleague to RGCC (Research Genetic Cancer Centre) testing. The blood test, also known as the "Greece Test" is a "liquid biopsy" that includes circulating tumor cell (CTC) detection, identification of phenotype biomarkers, chemosensitivity testing of cytotoxic agents and natural substances to cancer cells in peripheral blood circulation that provides scientific data for clinical personalization of cancer therapy.
To date, Dr. Donato has managed several thousand client cases in over 200 countries via Telehealth. He believes that the layered application of principles from science in molecular oncology within an integrative therapeutic framework over a platform of whole foods plant-based diet and lifestyle medicine leads to higher positive clinical outcomes in cancer therapy.
Dr. Donato takes the role of a client health advocate providing informed choices in healthcare. The client as a team member makes the final decision to follow a health path based on informed choices. Dr. Donato helps to coordinate and integrate the client's choice and interfaces therapy tasks from various healthcare providers into one integrative cancer therapy protocol.
To attain a level of consciousness that a healthy mind, body, and spirit is a balance that leads to a satisfying, happy, and joyful life, which is divinely inspired.
To reach the maximum positive clinical outcomes in therapy while maintaining an etiquette of practice that serves to satisfy societal expectations.
This is a live online video meeting consultation with Dr. Donato who will answer general questions regarding Gerson Therapy, RGCC testing, and distance-based case management services. Click Here to book the 30-minute appointment
This appointment will help determine if you are a good candidate for onboarding case management with Dr. Donato.
This is a live online video meeting consultation with Dr. Donato to go onboard case management. Current clinical signs, symptoms, and health status will be reviewed along with blood labs, imaging, and pathology report. Discussion will include therapy strategies, expectations, and nutritional metabolic therapy protocol. Dr. Donato will explain how the therapy protocol works. Click Here to book the 1 hour appointment.
If you have significant functional impairment and are not sure you are a good candidate to go onboard case management, please select the above Question & Answer Session appointment first. You can also Click Here.
After you book the New Client Initial Consult, follow the 5 Steps to Come Onboard as a Client for Case Management below.
This live online video meeting consultation with Dr. Donato is a service for anyone in the United States, Canada and United Kingdom interested in ordering RGCC testing. You are not required to become an established client of Dr. Donato to order the testing. There are many types of RGCC tests available. Dr. Donato will explain the purpose of each test so you can choose the right one for your health condition. The RGCC test order will be processed during the meeting. Click Here to book the 20-minute appointment.
RGCC Test Price:
Click here to see the approximate test price. The actual price will differ slightly on the date of the test request.
IMPORTANT: After booking the appointment, Click Here to download and complete the RGCC Intake Form (the form is fillable in your computer or device) and then Click Here to upload and send securely to Dr Donato LLC. Information from the RGCC Intake Form will be used to create an RGCC client account for Dr Donato LLC to order the test.
This live online video meeting consultation with Dr. Donato is a service for an Established Client in the United States, Canada and United Kingdom needing a follow-up RGCC testing. The RGCC test will be ordered and a RGCC test kit shipped to the client's address on file.
Click the appropriate link from the choices below associated with the follow-up test to book the 1 Hr follow-up appointment. Allow 4 weeks in advance from today to select the date for the follow-up appointment when scheduling.
Click Here for OncoTrace test follow-up appointment
Click Here for OncoTrail test follow-up appointment
Click Here for Onconomics Plus follow-up appointment
Click Here for Onconomics Extracts+ test follow-up appointment
RGCC Test Price:
The actual test price varies by a few dollars from day to day due to changes in exchange rates from Euro to USD. The USD test price includes the test kit. Click Here to see the approximate test price. The actual price will differ slightly on the date of the test request.
This is a live online video meeting consultation with Dr. Donato for an Established Client who has questions about the assigned therapy protocol following the New Client Initial Consult or for any questions.
Click Here to book a 15-minute appointment.
Click Here to book a 30-minute appointment.
This is a live online video meeting consultation with Dr. Donato for RGCC Test Analysis, Detailed Interpretation and Explanation with commentary on PAST or CURRENT test results. This service is intended for those who do not fully understand the test results and how the results are applied.
Select the specific RGCC test interpretation to book a consultation:
OncoTrace or OncoTrail Test: Click Here
Onconomics Extracts Test: Click Here
Onconomics Extracts+ Test: Click Here
Onconomics Plus Test: Click Here
OncoTrace or OncoTrail + Onconomics Plus Tests: Click Here
OncoTrace or OncoTrail + Onconomics Extracts+ Tests: Click Here
After booking a consultation, Click Here to upload the RGCC test results securely to Dr Donato LLC.
This is a live online video meeting consultation with Dr. Donato for Routine Blood Lab Analysis, and Interpretation of CURRENT test results only. This service is intended for those who do not fully understand the routine blood test results.
Click Here to book a consultation.
After booking a consultation, Click Here to upload the blood test results securely to Dr Donato LLC.
Download the pdf Intake Form to your computer from the link below. Open the document in your computer. Turn on the Autofill feature in the pdf document and complete the form. Send the completed form securely to Dr Donato LLC, see Step 5 below. Note: if your computer does not have a pdf Autofill feature, print the form out and complete by hand, take a photo of each page and send securely to Dr Donato LLC in Step 5 below.
You can provide the document after the meeting if it is not yet accessible
If you do not have current lab test results (less than 4 weeks) for the baseline and need to order blood tests, follow the instructions below on "Ordering Your Own Baseline Blood Tests" or if you wish for your healthcare insurance to cover this you can request your medical doctor to order the baseline lab tests listed.
Radiology reports from PET/CT, CT, MRI, NM Whole Body Bone Scan, Ultrasound, Mammogram, or plain x-rays, if any.
Click the link below to upload the documents securely to Dr Donato LLC
Please ONLY send the requested documents using the secure link above in order to meet HIPAA requirements for privacy of information.
This service is available to anyone in the United States, Canada and United Kingdom ONLY. RGCC DOES NOT TEST for primary central nervous system tumors or basal cell carcinoma. You are not required to become an established client of Dr. Donato to request and order the testing. What you do with the test results is your full responsibility. It is strongly recommended that you consult with an RGCC practitioner to gain further explanation and understanding of the test results in order to be well-informed and to pursue the health path that is right for you.
Click Here to view the approximate price list established by RGCC International North America.
Click Here to view a video clip about the blood sample collection and shipping to the lab.
Click Here to download and complete the PDF fillable RGCC Intake Form in your computer or device (note: for Yes/No questions, click the appropriate box next to them). When completed, Click Here to open the secure ShareFile folder, fill in the prompted information and then upload the file securely. The file will go directly to Dr Donato LLC.
Scroll down to the test you wish to order and click the link. Please note the payment in the link is for the service performed by Dr Donato LLC
Following the service fee payment in Step 2, an email from Dr Donato LLC will be generated that will provide you with specific instructions in making the payment for the RGCC test. Click Here to view the approximate price list established by RGCC International North America. The actual price will differ slightly on the date of the test request. Donato LLC will process the test payment transaction directly to RGCC International North America on your behalf. For UK residents, an invoice will be sent from the local branch in Bristol.
Following payment transaction for the RGCC test, another email will be generated with the attached test payment receipt and the test order confirmation form. Print the Test Order Confirmation form to accompany the blood sample that is shipped to the RGCC lab. Complete instructions regarding blood collection, local blood draw location and shipping will be provided. The RGCC test kit will be drop shipped to your home or shipping address referenced from the Intake Form. For US and Canadian residents, it will take 4-8 days to deliver via FedEx Ground depending on proximity to the distribution center located in Atlanta, GA. For UK residents, the test kit will come from RGCC North & West LTD branch office located in Bristol.
Click Here to view a video clip for information about the blood sample collection and shipping to the lab.
Test results are released approximately 14-16 days after the test kit with the blood sample is dropped off at the FedEx store or hub. When the test results are released to Dr Donato LLC, the results will be forwarded immediately to you. An in-depth test interpretation consultation can be provided by Dr Donato LLC as an optional service or you can discuss the RGCC test results with a registered RGCC provider of your choice.
This is a CANCER SCREENING TEST for healthy individuals with no history of cancer diagnosis but with risks due to family history or vulnerability from environmental toxin exposure. This blood test will detect cancer whether there are symptoms or no symptoms.
Peripheral blood mononuclear cells are isolated from blood samples, and gene expression analysis is performed in more than 90 genes. Their expression profile analysis in combination with machine learning algorithms is then used for the classification of the sample as healthy or unhealthy.
The test is clinically validated and highly accurate: True Positive 92.40%, True Negative 94.78%.
Example of a Report Summary: "Your results indicate a positive reaction of your immune system (PBMC) to cancer cells."
Click Here to request for this test and then go to Step 3 above. Read about Onco-D-clare here. As a complimentary for ordering this test through Dr Donato LLC, a written commentary from Dr Donato regarding the test results will be added to the report. A recommendation as to potential steps to take will also be included if indicated.
Click Here for OncoTrace test request and then go to Step 3 above.
Read about OncoTrace here. This test is for individuals who have a cancer diagnosis, cancer of unknown primary, or who have a history of cancer that is in-remission. As a complimentary for ordering this test through Dr Donato LLC, a written interpretation with commentary from Dr Donato regarding the test results will be added to the report. A recommendation as to potential steps to take will also be included if indicated.
Click Here for OncoTrail test request and then go to Step 3 above.
Read about OncoTrail here. This test is for individuals who have a cancer diagnosis, cancer of unknown primary, or who have a history of cancer that is in-remission. As a complimentary for ordering this test through Dr Donato LLC, a written interpretation with commentary from Dr Donato regarding the test results will be added to the report. A recommendation as to potential steps to take will also be included if indicated.
Click Here for Onconomics Plus test request and then go to Step 3 above.
Read about Onconomics Plus here. This test is for an established cancer diagnosis.
Click Here for Onconomics Extracts+ test request and then go to Step 3 above.
Read about Onconomics Extracts+ here. This test is for an established cancer diagnosis.
Click Here for OncoTrace + Onconomics Plus test request and then go to Step 3 above.
This combo test is recommended if this is the first time RGCC testing is ordered for an established cancer diagnosis. Chemosensitivity test for oncology drugs, off-label drugs and sensitivity test for anti-cancer natural supplements.
Click Here for OncoTrace + Onconomics Extracts+ test request and then go to Step 3 above. This combo test is recommended if this is the first time RGCC testing is ordered for an established cancer diagnosis (please note the Onconomics Extracts+ tests for sensitivity to anti-cancer natural supplements and off-label drugs ONLY and DOES NOT include oncology drug chemosensitivity as the Onconomics Plus).
Nutritional Supplements
Comprehensive Wellness Profile (CWP): This bundled test consists of CBC with differential, Glucose, Electrolytes, Lipid Panel, Liver Panel, TSH, Kidney (metabolic panel), Mineral and Bone.
Inflammation Markers: CRP high sensitivity, ESR (sed rate), and Ferritin.
Vitamins: Vitamin B2 serum, Vitamin D 25 Hydroxy
Urinalysis, Complete with Microscopic Examination
Cancer Marker (below is a list of general cancer markers for biopsy-proven or established diagnosis of cancer ONLY and NOT for screening):
CA 27.29 or CA 15-3 (for Breast Cancer)
PSA (for Prostate Cancer)
CEA (for Colon Cancer or Lung Cancer)
CA 19-9 (for Pancreatic Cancer)
CA 125 (for Ovarian Cancer)
Thyroglobulin (for post-thyroidectomy Papillary Thyroid Cancer)
S100B (for metastatic Melanoma)
AFP (for Hepatocellular Liver Cancer)
Beta-2 Microglobulin (for Lymphoma or Leukemia)
CGA (for Neuroendocrine Cancer)
Doctors Orders Not Necessary. Dr. Donato uses DirectLabs, a large client of Quest Diagnostics that provides discounted lab testing to the public. To order the above listed baseline lab tests, Click Here
DirectLabs services not available in NJ, NY, and RI
Quest services not available in AZ
Note: When ordering the routine lab tests at checkout, you have the option of instructing DirectLabs to send the test results to Dr. Donato besides automatically receiving yours. Enter the email address DrDonato@pm.me
Please reach us at drdonato@pm.me if you cannot find an answer to your question.
RGCC stands for Research Genetic Cancer Centre. It was founded by medical oncologist and genetics researcher, Dr. Ioannis Papasotiriou, MD, PhD in 2004. RGCC is an oncology research and development company that has 25+ branches in 20+ countries, and the global presence is increasing. RGCC headquarters is in Switzerland and general lab in Greece. There are other labs in Germany and India that are for research purposes.
RGCC testing is a molecular oncology blood test also known as “liquid biopsy” that detects whole cancer cells (circulating tumor cells) disseminated from primary and/or metastatic sites or from unknown primary sites at very low level, and enabling enumeration for the baseline, and for identification of the heterogeneous cancer cell population. The test is not meant to replace current conventional diagnostics, but like imaging and routine blood work it provides a more accurate assessment of the cancer status when combined with routine imaging study and routine blood labs.
An analogy comparing conventional diagnostics with RGCC testing is as follows. When doing clinical imaging studies (PET/CT, CT, MRI, US, Mammogram scans) of the body, on one hand it is like looking down at a forest from a drone high above and seeing the landscape and the borders or perimeters of an area of interest but unaware of what is happening at the ground level under the canopy of the trees. RGCC testing on the other hand is like looking from the roots of the trees up to the ground level to see what is happening. The view from the drone can spot changes in the topography, shape, borders, and perimeters of the forest indicating suspicious activity below, but a closer look down at the ground level and roots of the trees may reveal a different situation. Combining the two information produces an accurate assessment of the area of interest for baseline and future comparisons.
When making clinical decisions and creating therapy plans, an assessment or clinical impression of the disease condition needs to be as accurate as possible. Conventional oncology diagnostics have relied on technologies that have not matched the growing molecular oncology diagnostics until recent years. Around 2015, advances in molecular oncology diagnostics introduced “liquid biopsy”, which involves whole blood studies of circulating tumor DNA (ctDNA) from circulating tumor cells (CTC) and cell-free DNA (cfDNA) released by cells into the blood. Detecting ctDNA and cfDNA enables early cancer diagnosis for conventional oncology. The process of determining specific treatment plan is based on the biopsy-proven cancer diagnosis and what the FDA has approved for treatment of that diagnosis.
Unlike detecting ctDNA and cfDNA, RGCC testing detects CTCs in the blood, identifies biomarkers that points to tissue of origin, risks (aggressive, resistance, recurrence, metastastasis) and chemosensitivity to determine the most effective therapeutic anti-cancer agents (drugs or natural supplements) against the cancer cells in-vitro. So, rather than creating a specific treatment plan based on biopsy-proven diagnosis, RGCC testing enables creation of personalized integrative therapy based on the individual's cancer cell physiology. There is no need to guess what works when using RGCC testing. The testing also provides the information on CTC resistance to treatment factors and tumor related gene expression rates (mutated genes that support cancer proliferation) for further customization of personalize therapy. Currently 171 anti-cancer agents are tested routinely, and additional agents can be added to the blood sample for chemosensitivity testing at the discretion of the practitioner.
Integrating and correlating RGCC testing data with conventional oncology diagnostics and application of conventional and/or holistic therapy enables maximum potential for positive clinical outcomes in oncology care.
Click Here to see comparison chart
RGCC International is in Zug, Switzerland
Click Here to read about the various tests available.
During the RGCC Test Order Consult Dr. Donato will initiate a request to RGCC North America distribution center in Atlanta, GA to drop ship a RGCC test kit to your home address (for North America residents only) via FedEx Ground. Delivery takes 4-8 days depending on location. The test kit contains a disposable blood draw kit, a vial containing EDTA to collect the blood sample, collection and shipping instructions and international paperwork (mostly pre-filled except your name, signature and date of blood draw), and a pre-paid FedEx International Priority shipping label. Blood draw service is either through AnyLabTestNow center (if available in your area) or via local mobile phlebotomy service. The test kit with the collected blood sample is taken to a local FedEx Store or hub to ship. Turn around time for test results averages 14-16 days. Results will be forwarded to you by Dr. Donato.
Click Here to view a video clip about the RGCC blood collection and shipping to the lab.
Literature References for Validity, Precision, Accuracy, and Methodology of RGCC Testing
Liquid Biopsy Review Articles:
CTC Detection and Isolation using Negative Selection Method:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631028/ https://www.intechopen.com/chapters/51880 https://www.akadeum.com/technology/positive-selection-vs-negative-selection/?cn- reloaded=1 https://karger.com/cpb/article/40/3-4/411/74763/Evaluation-of-Isolation- Methods-for-Circulating https://www.cell.com/iscience/pdf/S2589-0042(22)00968-3.pdf
Chemosensitivity Assays using Liquid Biopsy of Melanoma CTCs:
https://rgcc-international.com/wp-content/uploads/2020/03/CTC-mel-BMC-2020.pdf
CTC Detection in Breast Cancer Patients:
https://rgcc-international.com/wp-content/uploads/2019/08/JCT_2019082714362025.pdf
CTC Analysis as Diagnostic Tool for Chemotherapy Response:
https://rgcc-international.com/wp-content/uploads/2019/06/Poster-2018-lisbon.pdf
CTCs to monitor disease progression and possible metastatic potential:
https://rgcc-international.com/wp-content/uploads/2019/06/Poster-2018-lisbon.pdf
Prediction of Metastases through study of CTCs:
Review Article of Liquid Biopsy in Diagnosis and Prognosis of Colorectal Cancer:
https://lupinepublishers.com/cancer-journal/pdf/OAJOM.MS.ID.000199.pdf
Real-life Precision of Liquid Biopsy selecting drugs compared to Tissue Biopsy:
https://link.springer.com/content/pdf/10.1007/s00432-020-03156-3.pdf
Gene expression profiling that supports the Onco-D-Clare cancer screening test for healthy subjects: https://rgcc-international.com/wp-content/uploads/2019/06/Oncotarget.pdf
Study showing contribution of WBC gene expression in prediction of cancer (supporting the introduction of Onco-D-Clare cancer screening test for healthy subjects): https://rgcc-international.com/wp-content/uploads/2020/07/Binder1-abstract-1.pdf
Treatment based on Tumor Related Gene Expression:
Gene Expression analysis in CTCs with Colorectal Cancer compared with established protocols: https://rgcc-international.com/wp-content/uploads/2023/07/Poster-ESMO-GI-2023.pdf
Cell Culturing Assays:
Comparison of Cell Culturing Assays:
https://rgcc-international.com/wp-content/uploads/2019/07/JCT_2019072315145979.pdf
Click Here to read more on RGCC research publication.
The Gerson Therapy is a nutritional metabolic therapy started by Dr. Max Gerson, MD in the 1920s, initially as a treatment for migraines. Later the Gerson Therapy started to be used for other chronic diseases like tuberculosis. It became famous world-wide as an anti-cancer therapy. It does not cure cancer but enables the human body to heal chronic degenerative diseases including cancer over time by changes in the internal body microenvironment through diet and lifestyle changes. For very advanced diseases, the therapy may need to be integrated with other healing methods including conventional treatments.
It is important to note that the FDA has never approved the Gerson Therapy as a cancer treatment. The traditional conventional healthcare does not support this form of therapy for any sick person. However, the Gerson Therapy has been around a very long time and there are many testimonials of diseases that were healed. The therapy is not recommended for everyone and anyone who wants to do the Gerson Therapy should do extensive reading and research to increase understanding of the therapy, indications, and contraindications.
The Gerson Therapy is a home-based program that utilizes a strict plant-based diet for a period, and that includes fresh vegetable juices that is pesticide-free and organically grown as a fundamental platform to address nutritional deficiencies or malnutrition, to change the internal body environment to support reversal of chronic degenerative diseases and to support the restoration of the body systems to normal function. Among the most important body systems are the energy system and immune system.
Also fundamental in the Gerson Therapy is the elimination or purging (detoxification) of the body toxins or poisons accumulated from years of exposure to environmental toxins that hinder optimal healing and repair. The Gerson coffee enema is the gold standard in detoxification of the body.
In addition, the Gerson Therapy utilizes nutritional supplements aimed at temporarily boosting the weakened or deficient energy system, supporting the liver function, and mobilizing toxins to eliminate from the body by using a methodology of salt and water management.
You can read more about Gerson Therapy by going to Gerson.org.
Click Here to listen to an interview of Gerson Practitioners and learn what they do for their clients.
There are 3 types of positive clinical outcomes:
1. Stability of disease. This means the disease has stopped progressing. The symptoms have not worsened and is manageable. A person can live a long time at this stage with continued therapy.
2. Partial improvement. This means the disease has reduced or a malignant tumor has shrunk but did not disappear. The symptoms have improved, and body functions may have almost normalized.
3. No evidence of disease. This means the disease is no longer detected by conventional diagnostic study. There are no symptoms. Body function is normal. In essence the disease is in remission.
The services offered by Dr. Donato, LLC is not to diagnose, treat, or cure a disease. Dr. Donato does not give medical advice. If you need a medical diagnosis and treatment, or if you have an urgent medical condition that needs medical care, please consult your primary care doctor.
In addition to providing services in the US and International, Dr Donato is also a registered out-of-state Telehealth Provider for Whole Family Healthcare in Winter Park, Florida
Secure Encrypted Email: DrDonato@pm.me
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